These can treat high blood pressure and edema. Thiazide-like diuretics: Examples include chlorthalidone and hydrochlorothiazide. When diuretics are used to help the kidneys get rid of more fluid, they can do so by changing the amount of sodium, chloride, and/or potassium, which either stay in the kidney or leave in the urine. Diuretics are often thought to cause leg cramps by affecting electrolyte levels, but a frequency hasn’t been specified. These are usually used to treat conditions like heart failure, high blood pressure, and edema - a type of fluid buildup. Potassium-sparing diuretics: Examples include triamterene (Dyrenium), spironolactone (Aldactone) and eplerenone (Inspra). Lastly, recent research suggests that statins might cause calcium to leak from muscle cells, and in turn, cause muscle pain. In addition, statins can contribute to lower levels of CoQ10 - an enzyme that helps our cells (and muscles) produce energy. Depending on a person’s genes, they might be more likely to experience muscle pain, including leg cramps, as a result of taking statins. While the exact reason why statins may cause muscle cramps is unknown, possible factors include genetics, coenzyme Q10 (CoQ10) levels, and calcium leakage. These can include:Ĭholesterol-lowering medications: Examples include atorvastatin (Lipitor), simvastatin (Zocor), and rosuvastatin (Crestor). Although the list below is not exhaustive, it covers many of the common offenders. Various medications are thought to cause - or raise the chances - of getting leg cramps at night. Which medications can cause leg cramps at night? We’ll talk about which medications and health conditions can result in leg cramps at night in more detail next. Some medications with side effects that can cause or lead to leg cramps Select health conditions like diseases of the blood vessels (vascular disease), cirrhosis, pregnancy, and other medical conditions. Muscle fatigue or certain types of nerve dysfunction (irregularities), which can contribute to leg painĮlectrolyte imbalances involving low levels of magnesium, potassium, or calcium Nonetheless, there are a few reasons why leg cramps may happen at night, including: They can perform physical and laboratory tests to help determine why you’re having them. To determine the specific reason you might be affected by them, it’s best to speak to your healthcare provider. Unfortunately, the specific cause of leg cramps at night has yet to be proven. In this article, we’ll discuss what causes leg cramps at night, how to treat them, and what other steps you can take to better manage them. Some medications may be able to help, and other supportive options - such as massages and sports drinks - are also available. Stretching the affected muscles may occasionally relieve these cramps, but sometimes other treatments are needed. But about 20% of people who have nightly leg cramps have moderate to severe symptoms that require some form of treatment or medical attention. In many cases, leg cramps at night are self-treatable or go away on their own. Leg cramps are characterized by sudden muscle tightness, typically in the calf, that may last seconds to minutes. They’re also commonly known as a charley horse or muscle spasm, and they’re reported to happen in about half of all adults over 50 years. Leg cramps at night - officially known as nocturnal leg cramps - are a common cause of leg pain that can disrupt sleep.
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